Changes in the Levels of Some Biochemical Parameters in the Serum of Children in Response to the Giardiasis Infection

Sarmad N. Mageed

doi:10.14500/aro.10518

Sarmad N. Mageed Department of Medical Microbiology, Faculty of Science and Health, Koya University, Daniel Mitterrand Boulevard, Koya KOY45, Kurdistan Region – F.R. Iraq http://orcid.org/0000-0001-5754-5544

Keywords: Biochemical parameters, Children, Giardiasis, Males and females

Abstract

Giardiasis is one of the most common intestinal protozoan infections worldwide. The study aimed to determine the levels of a number of biochemical parameters in the sera of children with giardiasis without receiving any medication for the treatment of giardiasis or intestinal helminthic infections in the previous 7 days. The study conducted 34 (19 females and 15 males) children and 34 (18 females and 16 males) healthy children as a control group. The mean ages of infected children and control groups were 8 ± 2 and 7 ± 2 years, respectively. Serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatinine, urea, sodium, potassium, uric acid, and albumin were determined. AST level in males was significantly higher than healthy children control (14.20 ± 1.896 and 10.06 ± 0.699), respectively (P < 0.05), and no significant difference in females was noticed whereas the significant increases in ALT level were found when compared to control (12.43 ± 0.806 and 8.666 ± 0.449), for female, respectively, whereas no significant change in males was observed. Creatinine levels showed significant decrease in females when compared to control (57.72 ± 1.170 and 73.37 ± 1.635) (P ≤ 0.001), respectively.

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Author Biography

Sarmad N. Mageed, Department of Medical Microbiology, Faculty of Science and Health, Koya University, Daniel Mitterrand Boulevard, Koya KOY45, Kurdistan Region – F.R. Iraq

Sarmad N. Mageed is an academic staff at the Department of Medical Microbiology, Faculty of Science and Health, Koya University, since 2004. He has a B.Sc. degree in Biology, M.Sc. degree in Parasitology and Ph.D. degree in Molecular Biology and Biochemistry of Parasites. Dr. Mageed has many scientific publications; (4) Journal Articles and (1) conference paper. He is Permanent Member of the British Society for Parasitology. Dr. Mageed has an extensive experience in cell culturing, antimicrobial chemotherapy and drug discovery technique skills, as well as DNA analysis and bioinformatics, cloning, biochemical pathway analysis, RNA purification, restriction enzyme analysis, and fluorimetry techniques. In addition, Dr. Mageed has sufficient knowledge and skills of microscopy, parasite identification, water and food-borne parasitic diseases and pathology of parasitic infections. He has also adequate experience of molecular laboratory skills, including Molecular Biology techniques, sequencing and gene modifying.

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