Moderate Range Static Magnetic Field Promoted Variation of Blood Parameters: An In vitro Study
Abstract
This study was undertaken to investigate the influence of a homogenous and uniform static magnetic field (SMF) on the main blood cell counts in vitro experiment. Fresh blood samples were collected from albino rats and exposed to SMF (2.4, 6, 25, 50, 75, and 100 mT) versus 15–60 min. Results showed a significant change of blood counts under the low field effects. A 2.4 mT was a trend of white blood cells (WBCs) count increase non-linearly. However, a 6 mT exposure reduced WBCs with about 39%. Other variations fluctuated within 30%. The 25 mT decreased red blood cells (RBCs), hemoglobin, and hematocrit levels with 13% similarly. The lower exposure field, (2.4 and 6) mT, and effects on RBCs were 6% fluctuation. The 6 mT reduced platelet counts with half in comparison to control blood samples. About 20% increase obtained due to 50 mT exposure during all period. None of 75 and 100 mT exposures dominated blood counts alterations. The quiet magnetic field exposure for a certain time can be interesting to control blood cell count-related diseases.
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Aida, L., Soumaya, G., Myriam, E., Mohsen, S. and Hafedh, A., 2014. Effects of static magnetic field exposure on plasma element levels in rat. Biological Trace Element Research, 160, pp.67-72.
AL-Dulaimi, K., Banks, J., Chandran, V., Tomeo-Reyes, I. and Nguyen, K., 2018. Classification of white blood cell types from microscope images: Techniques and challenges. In: Microscopy Science: Last Approaches on Educational Programs and Applied Research. Formatex Research Center, Spain, pp.17-25.
Blann, A., 2014. Functions and diseases of red and white blood cells. Nurs Times, 110, pp.16-18.
Chadwick, P. and Lowesf, F., 1998. Magnetic fields on british trains. Annals Occupational Hygiene, 42, pp.331-335.
Chater, S., Abdelmelek, H., Pequignot, J.M., Sakly, M. and Ben Rhouma, K., 2006. Effects of sub-acute exposure to static magnetic field on hematologic and biochemical parameters in pregnant rats. Electromagnetic Biology Medicine, 25, pp.135-144.
Djordjevich, D.M., Luka, S.R. De, Milovanovich, I.D., Andjelija, Z., Stefanovic, S., Trbovich, A.M. and Ristic, J.L., 2012. Ecotoxicology and environmental safety hematological parameters’ changes in mice subchronically exposed to static magnetic fields of different orientations. Ecotoxicology Environmental Safety, 81, pp.8-105.
Hashish, A.H., El-Missiry, M.A., Abdelkader, H.I. and Abou-Saleh, R.H., 2008. Assessment of biological changes of continuous whole body exposure to static magnetic field and extremely low frequency electromagnetic fields in mice. Ecotoxicology Environmental Safety, 71, pp.895-902.
Ismail, A.H., 2015. Influence of radiation doses on the ratio of blast cells, lymphocytes and neutrophils inside blood samples of leukaemia patients: In vitro. ZANCO Journal of Pure and Applied Sciences, 27(3), pp.65-74.
Italiano, J.E., 2007. The structure and production of blood platelets. In: Platelets in Hematologic and Cardiovascular Disorders. Cambridge University Press, Cambridge, United Kingdom, pp.1-20.
Najam, L., AL-Dulamey, Q., and Al-Jawwady, Y., 2020. Effects of low dose gamma ray on some hematological parameters in adult rats. Iranian Journal of Medical Physics, 17(3), pp.137-141.
Maulood, K.A., 2018. Assessment of some hematological, biochemical parameters and cardiac biomarker levels in patients with ischemic heart disease in Erbil city. Zanco Journal of Pure Applied Sciences, 30, pp.86-93.
Milovanovich, I.D., Luka, S.R. De, Djordjevich, D.M., Ili, A.Ž., Popovi, T., Arsi, A., Obradovi, D.D., Opri, D., Risti, J.L. and Trbovich, A.M., 2016. Homogeneous static magnetic field of different orientation induces biological changes in subacutely exposed mice. Environmental Science and Pollution Research International, 23, pp.1584-1597.
Mustafa, B.T., Yab, S.P. and Ismail, A.H., 2020a. Impacts of materials on the intensity of uniform static magnetic fields using a multi Helmholtz coils design. AIP Conference Proceedings, 2213(1), pp.020063.
Mustafa, B.T., Yaba, S.P. and Ismail, A.H., 2019. A review of the effects of magnetic field on main blood cells : In vivo and in vitro experiments. ZANCO Journal of Pure and Applied Sciences, 31(6), pp.40-50.
Mustafa, B.T., Yaba, S.P. and Ismail, A.H., 2020b. Influence of static magnetic field on red blood cells parameters and platelets using tests of CBC and microscopy images. Biomedical Physics and Engineering Express, 6(2), pp.025004.
Okano, H. and Ohkubo, C., 2005. Effects of neck exposure to 5.5 mT static magnetic field on pharmacologically modulated blood pressure in conscious rabbits. Bioelectromagnetics, 26, pp.469-480.
Sahebjamei, H., Abdolmaleki, P. and Ghanati, F., 2007. Effects of magnetic field on the antioxidant enzyme activities of suspension-cultured tobacco cells. Bioelectromagnetics, 28, pp.42-47.
Sihem, C., Hafedh, A., Mohsen, S., Marc, P.J. and Khmais, B.R., 2006. Effects of sub-acute exposure to magnetic field on blood hematological and biochemical parameters in female rats. Turkish Journal of Hematology, 23(4), pp.182-187.
Strieth, S., Strelczyk, D., Eichhorn, M.E., Dellian, M., Luedemann, S., Griebel, J., Bellemann, M., Berghaus, A. and Brix, G., 2008. Static magnetic fields induce blood flow decrease and platelet adherence in tumor microvessels. Cancer Biology and Therapy, 7, pp.632-637.
Sweetnam, P.M., Thomas, H.F., Yarnell, J.W.G., Baker, I.A. and Elwood, P.C., 1997. Total and differential leukocyte counts as predictors of ischemic heart disease: The caerphilly and speedwell studies. American Journal of Epidemiology, 145, pp.416-421.
Van Deventer, T.E., Saunders, R. and Repacholi, M.H., 2005. WHO health risk assessment process for static fields. Progress in Biophysics and Molecular Biology, 87, pp.355-363.
Vergallo, C. and Dini, L., 2018. Comparative analysis of biological effects induced on different cell types by magnetic fields with magnetic flux densities in the range of 1-60 mT and frequencies up to 50 Hz. Sustainability, 10(8), pp.2776.
World Health Organization, 2006. Static fields, Environmental Health Criteria. Geneva: World Health Organization.
Yamagishi, A., 1990. Biological systems in high magnetic field. Journal of Magnetism and Magnetic Materials, 90-91, pp.43-46.
Zapata, J.C., Cox, D. and Salvato, M.S., 2014. The role of platelets in the pathogenesis of viral hemorrhagic fevers. PLoS Neglected Tropical Diseases, 8, pp.e2858.
Zhao, G., Chen, S., Wang, L., Zhao, Y., Wang, J., Wang, X., Zhang, W.W., Wu, R., Wu, L., Wu, Y. and Xu, A., 2011. Cellular ATP content was decreased by a homogeneous 8.5 T static magnetic field exposures Role of reactive oxygen species. Bioelectromagnetics, 32, pp.94-101.
Copyright (c) 2020 Bestoon T. Mustafa; Sardar P. Yab; Asaad H. Ismail
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