Ultrasound-assisted Synthesis of Some New Curcumin Analogues and Their Corresponding Pyrazoline Derivatives

Farouq E. Hawaiz, Dlzhen A. Shekh Omer

Abstract


In this work, a series of new curcumin mono-carbonyl analogs containing benzyloxy moieties and their pyrazoline derivatives were synthesized using a green method (ultrasound assisted technique) along with traditional method.  The work also includes a comparison between the two methods together and with literature.  Remarkable improvements were achieved by dropping down the reaction time from hours to minutes and obtaining higher yields of the products. 


Keywords


Curcumin, Mono carbonyl curcumins, Pyrazoline, Ultrasound.

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DOI: http://dx.doi.org/10.14500/aro.10149
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